The formation of a new eight member league was announced in January 1957. The Mid-State Conference included seven members who withdrew from the Big Black Conference and one other school. The newly formed league began with eight original members who would compete in football that fist season.
        The league disbanded following the 1963 football season.

         

Mid-State Conference Champions
1963	Ackerman	1959	Durant
1962		1958	Lexington
1961	Durant	1957
1960	Durant