The Pascagoula River Conference was formed in 1963. The newly formed league began with six original members all along the Mississippi gulf coast.

         

Pascagoula River Conference Champions
1980	Vancleave	1971
1979	D'Iberville	1970
1978	D'Iberville	1969
1977	D'Iberville	1968	D'Iberville
1976		1967	East Central
1975	Pass Christian	1966	Saint John
1974	Pass Christian	1965	Our Lady Victory
1973	Vancleave	1964
1972	East Central	1963	Agricola