| 2024 |
| Fri., Nov. 1 | vs. Central Holmes Christian | W 42-0 | 1st Round Playoffs | | Fri., Nov. 8 | @ Canton Academy | W 22-14 | 2nd Round Playoffs | | Fri., Nov. 15 | @ Kirk Academy | L 30-34 | Semi-finals Playoffs |
| 2023 |
| Fri., Oct. 27 | Bye | - | 1st Round Playoffs | | Fri., Nov. 3 | vs. North Delta | W 45-6 | 2nd Round Playoffs | | Fri., Nov. 10 | @ Canton Academy | W 28-27 | Semi-finals Playoffs | | Fri., Nov. 17 | Kirk Academy | W 6-0 | Championship Game |
| 2022 |
| Fri., Oct. 28 | Bye | - | 1st Round Playoffs | | Fri., Nov. 4 | vs. Carroll Academy | W 48-0 | 2nd Round Playoffs | | Fri., Nov. 11 | vs. Riverfield LA | W 46-0 | Semi-finals Playoffs | | Thu., Nov. 17 | Tri-County Academy | W 26-14 | Championship Game |
| 2021 |
| Fri., Nov. 5 | vs. Indianola Academy | W 41-20 | 2nd Round Playoffs | | Fri., Nov. 12 | vs. Tri-County Academy | L 7-14 | Semi-finals Playoffs |
| 2020 |
| Fri., Oct. 30 | vs. Tunica Academy | W 35-0 | 1st Round Playoffs | | Fri., Nov. 6 | vs. Sylva Bay Academy | W 42-7 | 2nd Round Playoffs | | Fri., Nov. 13 | @ Carroll Academy | L 6-15 | Semi-finals Playoffs |
| 2019 |
| Fri., Nov. 8 | vs. Central Holmes Christian | W 42-27 | 2nd Round Playoffs | | Fri., Nov. 15 | vs. Carroll Academy | W 20-18 | Semi-finals Playoffs | | Fri., Nov. 22 | Indianola Academy | W 55-24 | Championship Game |
| 2018 |
| Fri., Oct. 26 | vs. Glenbrook LA | W 52-7 | 1st Round Playoffs | | Fri., Nov. 2 | vs. Clinton Christian | W 26-20 | 2nd Round Playoffs | | Fri., Nov. 9 | vs. Brookhaven Academy | W 40-0 | Semi-finals Playoffs | | Sat., Nov. 17 | Centreville Academy | W 42-22 | Championship Game |
| 2017 |
| Fri., Oct. 27 | vs. Winona Christian | W 44-0 | 1st Round Playoffs | | Fri., Nov. 3 | @ Manchester Academy | W 35-0 | 2nd Round Playoffs | | Fri., Nov. 10 | @ Centreville Academy | W 33-14 | Semi-finals Playoffs | | Thu., Nov. 16 | Tri-County Academy | W 44-14 | Championship Game |
| 2016 |
| Fri., Oct. 28 | vs. Central Private LA | W 46-3 | 1st Round Playoffs | | Fri., Nov. 4 | @ Centreville Academy | W 42-0 | 2nd Round Playoffs | | Fri., Nov. 11 | @ Adams Christian | L 20-36 | Semi-finals Playoffs |
| 2015 |
| Fri., Oct. 30 | vs. Leake Academy | L 18-19 | 1st Round Playoffs |
| 2014 |
| Fri., Nov. 14 | @ Coffeeville | L 14-63 | 1st Round Playoffs |
| 2012 |
| Fri., Nov. 9 | @ Smithville | W 38-6 | 1st Round Playoffs | | Fri., Nov. 16 | vs. French Camp Academy | L 18-31 | 2nd Round Playoffs |
| 2011 |
| Fri., Nov. 11 | @ Vardaman | L 21-35 | 1st Round Playoffs |
| 2009 |
| Fri., Nov. 13 | @ Okolona | L 21-64 | 1st Round Playoffs |
| 2008 |
| Fri., Nov. 14 | vs. Calhoun City | L 14-53 | 1st Round Playoffs |
| 2007 |
| Fri., Nov. 16 | @ Okolona | W 9-7 | 1st Round Playoffs | | Fri., Nov. 23 | vs. Brooks | L 0-30 | 2nd Round Playoffs |
| 2006 |
| Fri., Nov. 10 | @ Vardaman | L 14-56 | 1st Round Playoffs |
| 1996 |
| Fri., Nov. 15 | @ Ruleville Central | L 12-22 | 1st Round Playoffs |
| 1993 |
| Fri., Nov. 12 | vs. Broad Street | W 35-34 | 1st Round Playoffs | | Fri., Nov. 19 | @ Calhoun City | L 7-27 | 2nd Round Playoffs |
| 1992 |
| Fri., Nov. 13 | vs. Okolona | L 27-28 | 1st Round Playoffs |
| 1991 |
| Fri., Nov. 15 | vs. Bruce | L 36-43 | 1st Round Playoffs |
| 1990 |
| Fri., Nov. 9 | vs. Ackerman | W 21-20 | 1st Round Playoffs | | Fri., Nov. 16 | vs. Okolona | L 8-37 | 2nd Round Playoffs |
| 1989 |
| Fri., Nov. 10 | @ Okolona | L 7-16 | 1st Round Playoffs |
| 1981 |
| | Sturgis | L 0-33 | 1st Round Playoffs |
|
| Saint Joseph Greenville Playoff Totals |
| Record |
28-19-0 1285-960 |
| Home Record | 16-8 |
| Away Record | 7-10 |
|
