| 2024 |
| Fri., Nov. 1 | @ Cumberland | L 6-28 | 1st Round Playoffs |
| 2023 |
| Sat., Oct. 28 | @ Althoff Catholic | L 41-76 | 1st Round Playoffs |
| 2022 |
| Sat., Oct. 29 | vs. Brown County | W 20-18 | 1st Round Playoffs | | Sat., Nov. 5 | vs. Routt Catholic/Lutheran | W 29-26 | 2nd Round Playoffs | | Sat., Nov. 12 | @ Ridgeview/Lexington | L 6-41 | 3rd Round Playoffs |
| 2019 |
| Sat., Nov. 2 | vs. Flora | W 42-14 | 1st Round Playoffs | | Sat., Nov. 9 | @ St. Teresa | L 20-63 | 2nd Round Playoffs |
| 2018 |
| | vs. Villa Grove | W 42-6 | 1st Round Playoffs | | | vs. Bismarck | W 42-21 | 2nd Round Playoffs | | | @ Maroa | L 28-63 | 3rd Round Playoffs |
| 2017 |
| | vs. Chester | W 56-0 | 1st Round Playoffs | | | @ Mt. Sterling | W 50-13 | 2nd Round Playoffs | | | vs. Carrollton | W 48-20 | 3rd Round Playoffs | | | @ Athens | W 21-14 | Semi-finals Playoffs | | | @ Lena | L 20-21 | Championship Game |
| 2016 |
| | vs. Oblong | W 52-7 | 1st Round Playoffs | | | @ Carrollton | W 55-28 | 2nd Round Playoffs | | | vs. Hardin | L 27-28 | 3rd Round Playoffs |
| 2015 |
| | vs. Camp Point | W 49-7 | 1st Round Playoffs | | | @ LeRoy | L 13-20 | 2nd Round Playoffs |
| 2014 |
| | @ Shelbyville | W 28-19 | 1st Round Playoffs | | | vs. Lawrenceville | W 28-21 | 2nd Round Playoffs | | | @ Chester | W 17-14 | 3rd Round Playoffs | | | @ Maroa | L 20-22 | Semi-finals Playoffs |
| 2013 |
| | @ Maroa | L 2-38 | 1st Round Playoffs |
| 2011 |
| | vs. Cerro Gordo | W 42-0 | 1st Round Playoffs | | | @ Moweaqua | W 31-6 | 2nd Round Playoffs | | | vs. Arcola | W 42-7 | 3rd Round Playoffs | | | @ Mt. Sterling | W 33-14 | Semi-finals Playoffs | | | @ Dakota | L 27-41 | Championship Game |
| 2010 |
| | vs. Carrollton | W 35-0 | 1st Round Playoffs | | | @ Moweaqua | W 54-36 | 2nd Round Playoffs | | | vs. Jacksonville | W 35-14 | 3rd Round Playoffs | | | @ Mt. Sterling | W 17-10 (OT) | Semi-finals Playoffs | | | vs. Lena | L 14-47 | Championship Game |
| 2009 |
| | Toledo | W 16-0 | 1st Round Playoffs | | | Mt. Sterling | W 21-18 | 2nd Round Playoffs | | | Astoria | W 38-0 | 3rd Round Playoffs | | | Jacksonville | W 21-7 | Semi-finals Playoffs | | | Lexington | W 14-7 | Championship Game |
| 2008 |
| | Jacksonville | W 31-12 | 1st Round Playoffs | | | Mt. Olive | W 21-7 | 2nd Round Playoffs | | | Concord | L 21-22 | 3rd Round Playoffs |
| 2007 |
| | Carrollton | W 60-0 | 1st Round Playoffs | | | Concord | W 62-8 | 2nd Round Playoffs | | | Mt. Olive | W 49-27 | 3rd Round Playoffs | | | Arcola | W 48-6 | Semi-finals Playoffs | | | Galena | L 7-35 | Championship Game |
| 2006 |
| | Fisher | W 23-6 | 1st Round Playoffs | | | Carrollton | W 34-8 | 2nd Round Playoffs | | | Arthur | W 24-3 | 3rd Round Playoffs | | | Mt. Olive | W 31-20 | Semi-finals Playoffs | | | Aledo | W 35-20 | Championship Game |
| 2005 |
| | Villa Grove | W 48-0 | 1st Round Playoffs | | | Lexington | W 41-0 | 2nd Round Playoffs | | | Fisher | W 33-0 | 3rd Round Playoffs | | | Cambridge 212.00 | L 21-42 | Semi-finals Playoffs |
| 2004 |
| | Fisher | W 33-7 | 1st Round Playoffs | | | Flanagan | W 44-38 | 2nd Round Playoffs | | | Arthur | L 7-36 | 3rd Round Playoffs |
| 2003 |
| | Argenta | L 19-35 | 1st Round Playoffs |
| 2002 |
| | Bridgeport | W 48-7 | 1st Round Playoffs | | | Moweaqua | L 12-14 | 2nd Round Playoffs |
| 2001 |
| | Farmer City | W 49-7 | 1st Round Playoffs | | | Sciota | L 15-28 | 2nd Round Playoffs |
| 2000 |
| | Williamsville | W 49-13 | 1st Round Playoffs | | | Sesser | W 39-14 | 2nd Round Playoffs | | | Tolono | L 14-41 | 3rd Round Playoffs |
| 1999 |
| | Dupo | W 35-7 | 1st Round Playoffs | | | Sesser | W 35-28 | 2nd Round Playoffs | | | Tolono | L 14-32 | 3rd Round Playoffs |
| 1998 |
| | Virden | L 20-39 | 1st Round Playoffs |
| 1997 |
| | Auburn | W 61-14 | 1st Round Playoffs | | | Monmouth | W 53-28 | 2nd Round Playoffs | | | Villa Grove | L 21-54 | 3rd Round Playoffs |
| 1996 |
| | Chester | W 49-8 | 1st Round Playoffs | | | Casey | W 28-21 (OT) | 2nd Round Playoffs | | | Moweaqua | L 14-40 | 3rd Round Playoffs |
| 1995 |
| | LeRoy | W 18-12 | 1st Round Playoffs | | | St. Teresa | L 0-41 | 2nd Round Playoffs |
| 1994 |
| | Heritage | L 24-25 | 1st Round Playoffs |
| 1988 |
| | Oakwood | L 13-14 | 1st Round Playoffs |
| 1987 |
| | Latham | L 7-14 | 1st Round Playoffs |
| 1986 |
| | Westfield | L 15-17 | 1st Round Playoffs |
| 1982 |
| | Oakwood | W 14-7 | 1st Round Playoffs | | | Casey | L 22-28 (OT) | 2nd Round Playoffs |
| 1976 |
| | Gibson City | L 22-29 | 1st Round Playoffs |
|
| Tuscola Playoff Totals |
| Record |
56-31-0 2585-1749 |
| Home Record | 14-2 |
| Away Record | 9-10 |
|
